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Class I PI 3-kinases
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Class I PI 3-kinases : ウィキペディア英語版
Class I PI 3-kinases
Class I PI 3-kinases are a subgroup of the enzyme family, phosphoinositide 3-kinase that possess a common protein domain structure, substrate specificity, and method of activation. Class I PI 3-kinases are further divided into two subclasses, class IA PI 3-kinases and class IB PI 3-kinases.
==Class IA PI 3-kinases==
Class IA PI 3-kinases are activated by receptor tyrosine kinases (RTKs).
There are three catalytic subunits that are classified as class IA PI 3-kinases:
*p110α
*p110β
*p110δ
*p110γ
There are currently five regulatory subunits that are known to associate with class IA PI 3-kinases catalytic subunits:
*p85α and p85β
*p55α and p55γ
*p50α

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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